Phytochemistry and Antibacterial Assessment of Ethyl acetate Leaf Extract of Newbouldia laevis

A current trend in drug research is the desire to obtain novel antimicrobials with plant origins as an alternative therapy and a means curb antimicrobial resistance. This study evaluated phytochemistry antibacterial activity of ethyl acetate leaf extract Newbouldia laevis. The laevis was cold extracted Ethyl acetate. for it phytochemical constituents using standard methods effect against some clinical bacterial isolates well diffusion technique. revealed presence phytochemicals, alkaloids, saponins, flavonoids, phenol, anthraquinones steroids extract, which were believed be contributing factor observed effects. test isolates' susceptibility crude measured at 25 mg/mL 50 mg/mL, 75mg/mL 100mg/mL. growth inhibition Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, Staphylococcus aureus Pseudomonas aeruginosa ranges from 9.66±1.54 13.00±0.00, 10.00±1.00 11.00±1.00, 9.33±0.57 14.00±0.00 17.33±1.52 10.66± 1.52 mm respectively. Minimum Inhibitory Concentration 25mg/mL, 12.5mg/mL, 25mg/mL,12.5mg/mL 25mg/mL respectively while Bactericidal Concentrations 50mg/mL, 50mg/mL effects due detected extract. results apparently justified traditional use this treating infections whose causative agents are organisms used study.